Test Name: ALT
EPIC Search Term: LABALT
Synonyms: ALANINE AMINOTRANSFERASE SGPT
Preferred Container: 1 x 0.6 mL Green Lithium Heparin with Gel Microtainer
Alternate Container: 1 x 0.6 mL Amber Microtainer with Gel
1 x 1 mL Green Lithium Heparin Tube with Gel
1 x 2 mL Red With Clot Activator
1 x 2 mL Green Lithium Heparin Tube without Gel
1 x 1 mL Red/Black Serum Separator (SST) Vacutainer
Sample Type: blood
Interfering Substances: Gross Hemolysis
Testing Frequency: Daily
Expected Turn Around Time: Same day
Clinical Application: Alanine aminotransferase (ALT) is present primarily in liver cells and is thus a more liver-specific enzyme. In viral hepatitis and other forms of liver disease associated with hepatic necrosis, serum ALT is elevated even before the clinical signs and symptoms of the disease appear. Serum elevations of ALT are rarely observed in conditions other than parenchymal liver disease.
In infectious hepatitis and other inflammatory conditions affecting the liver, ALT is characteristically as high as or higher than aspartate aminotransferase (AST), and the ALT:AST ratio, which normally and in other condition is less than 1, becomes greater than unity.

Caution: High levels of pyruvate may interfere with the assay
Reference Ranges: Age 0-3 years: Male: 12-45 Female: 14-45
Age 4-13 years: Male: 10-41 Female: 11-28
Age 14-18 years: Male: 11-26 Female: 10-35
Age >/=19 year: Male: <50 Female: 5-34


Unit of Measure: U/L
Test Performed By: Texas Children's Hospital Pathology Services

Available at TCH Main Campus: 832-824-5152
6621 Fannin, MC 1-2261
Houston, TX 77030-2399

Available at TCH Pavilion for Women: 832-826-7400
6651 S. Main St.
Houston, TX 77030

Available at TCH West Campus: 832-227-1700
18200 Katy Freeway
Houston, TX 77094

Available at TCH Woodlands Campus: 936-267-5200
17600 Interstate 45 South
The Woodlands, TX 77384
Lab Section: Chemistry